CASP9 Polyclonal Antibody
| Dodavatel: | Reddot Biotech USA Inc. | |||||||||||||||||||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||||||||||||||||||
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This is a CASP9 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
| Clonality | Polyclonal | |
| Purification Method | Affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Synthesized peptide derived from human Caspase-9 around the non-phosphorylation site of Thr125. | |
| Swissprot | P55211 | |
| Calculated MW | 46 kDa | |
| Observed MW | 46 kDa | |
| Reactivity | Human,Mouse,Rat | |
| Applications | WB,IHC-p,IF,ELISA | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000 | |
| Concentration | 1 mg/mL | |
| Buffer | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
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