AFViolet 450 Anti-Human IgD Antibody[IA6-2]

IgD, a member of the immunoglobulin (Ig) family, is expressed in na?ve B cells. It has 3 Ig-like domains and exists in a transmembrane and a soluble form. In general, IgD is not secreted and usually its expression is lost after the Ig isotype switch. After antigen binding, IgD signals through the CD79a/CD79b (Igα/Igβ) heterodimer, resulting in the activation of the B cell.