Rb Polyclonal Antibody
| Dodavatel: | Reddot Biotech USA Inc. | ||||||||||||||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | ||||||||||||||
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This is a Rb Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
| Purification Method | Affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Recombinant fusion protein of human Rb (NP_000312.2). | |
| Gene ID | 5925 | |
| Swissprot | P06400 | |
| Reactivity | Human | |
| Applications | IF | |
| Conjugation | Unconjugated | |
| Dilution | IF 1:50-1:200 | |
| Concentration | 1 mg/mL | |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
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