ADRM1 Polyclonal Antibody
| Dodavatel: | Reddot Biotech USA Inc. | |||||||||||||||||||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||||||||||||||||||
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This is a ADRM1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
The 26S proteasome is a key component of the ubiquitin-proteasome system,a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme,UCH37,and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.
| Clonality | Polyclonal | |
| Purification Method | Antigen affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Fusion protein of human ADRM1 | |
| Swissprot | Q16186 | |
| Gene Accession | BC017245 | |
| Reactivity | Human,Mouse,Rat | |
| Applications | IHC,ELISA | |
| Conjugation | Unconjugated | |
| Dilution | IHC 1:50-1:300, ELISA 1:5000-1:10000 | |
| Concentration | 1.26 mg/mL | |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
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