C5AR1 Polyclonal Antibody
| Dodavatel: | Reddot Biotech USA Inc. | |||||||||||||||||||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||||||||||||||||||
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This is a C5AR1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
| Clonality | Polyclonal | |
| Purification Method | Antigen affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Fusion protein of human C5AR1 | |
| Swissprot | P21730 | |
| Gene Accession | BC008982 | |
| Reactivity | Human | |
| Applications | IHC,ELISA | |
| Conjugation | Unconjugated | |
| Dilution | IHC 1:40-1:200, ELISA 1:5000-1:10000 | |
| Concentration | 0.7 mg/mL | |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
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