p63 Rabbit mAb

Dodavatel: Reddot Biotech USA Inc.
Teplota skladování: Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo: RDSA66869
Velikost balení: 100μL
Cena bez DPH: 8 964,00 Kč
Dostupnost: NA OBJEDNÁNÍ
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Zobrazovat ceny: bez DPH / včetně DPH
This is a p63 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis.
ClonalityMonoclonal
Purification MethodAffinity purification
IsotypeIgG
HostRabbit
ImmunogenA synthesized peptide derived from human p63
SwissprotQ9H3D4
ReactivityHuman,Mouse,Rat
ApplicationsWB,IHC,ICC/IF,FC
ConjugationUnconjugated
DilutionWB 1:500-1:2000, IHC 1:100-1:500, ICC/IF 1:50-1:200, FC 1:500
BufferPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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RDSA66869