PMS2 Rabbit mAb

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RDSA66520
Velikost balení:	100μL
Cena bez DPH:	8 964,00 Kč
Dostupnost:	NA OBJEDNÁNÍ

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Zobrazovat ceny: bez DPH / včetně DPH

This is a PMS2 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected.

Technická specifikace

Clonality		Monoclonal
Purification Method		Affinity purification
Isotype		IgG
Host		Rabbit
Immunogen		A synthesized peptide derived from human PMS2
Swissprot		P54278
Reactivity		Human
Applications		WB,IHC,ICC/IF,IP,FC
Conjugation		Unconjugated
Dilution		WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50, FC 1:50
Buffer		Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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PMS2 Rabbit mAb

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