PHD1/prolyl hydroxylase Rabbit mAb

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RDSA66499
Velikost balení:	100μL
Cena bez DPH:	8 964,00 Kč
Dostupnost:	NA OBJEDNÁNÍ

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Zobrazovat ceny: bez DPH / včetně DPH

This is a PHD1/prolyl hydroxylase Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Technická specifikace

Clonality		Monoclonal
Purification Method		Affinity purification
Isotype		IgG
Host		Rabbit
Immunogen		A synthesized peptide derived from human PHD1/prolyl hydroxylase
Swissprot		Q96KS0
Reactivity		Human,Mouse,Rat
Applications		WB,IHC,ICC/IF,FC
Conjugation		Unconjugated
Dilution		WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, FC 1:50
Buffer		Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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PHD1/prolyl hydroxylase Rabbit mAb

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