PHD2 / prolyl hydroxylase Rabbit mAb
| Dodavatel: | Reddot Biotech USA Inc. | |||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||
| Katalogové číslo: | RDSA65463 | |||
| Velikost balení: | 100μL | |||
| Cena bez DPH: | 8 964,00 Kč | |||
| Dostupnost: | NA OBJEDNÁNÍ | |||
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Vložit do košíku | |||
This is a PHD2 / prolyl hydroxylase Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
| Clonality | Monoclonal | |
| Purification Method | Affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | A synthesized peptide derived from human PHD2 / prolyl hydroxylase | |
| Swissprot | Q9GZT9 | |
| Calculated MW | 46kDa | |
| Reactivity | Human | |
| Applications | WB,IP | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:500-1:2000, IP 1:50 | |
| Buffer | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
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RDSA65463