DRP1 (Phospho-Ser637) Antibody

Dodavatel: Reddot Biotech USA Inc.
Teplota skladování: Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo: RDSA62484
Velikost balení: 100μL
Cena bez DPH: 9 274,00 Kč
Dostupnost: NA OBJEDNÁNÍ
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Zobrazovat ceny: bez DPH / včetně DPH
This is a DRP1 (Phospho-Ser637) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation.
ClonalityPolyclonal
Purification MethodAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
IsotypeIgG
HostRabbit
ImmunogenPeptide sequence around phosphorylation site of Serine637(K-L-S(p)-A-R) derived from Human DRP1.
Gene ID10059
SwissprotO00429
Observed MW82kDa
ReactivityHuman
ApplicationsWB
ConjugationUnconjugated
DilutionWB 1:500-1:1000
Concentration1.0 mg/mL
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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RDSA62484