PKA ɑ/β CAT (Phospho-Thr197) Antibody

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RDSA62380
Velikost balení:	100μL
Cena bez DPH:	9 274,00 Kč
Dostupnost:	NA OBJEDNÁNÍ

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This is a PKA ɑ/β CAT (Phospho-Thr197) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose-mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts.

Technická specifikace

Clonality		Polyclonal
Purification Method		Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Isotype		IgG
Host		Rabbit
Immunogen		Peptide sequence around phosphorylation site of threonine 197(T-W-T(p)-L-C) derived from Human PKA α/β CAT.
Gene ID		5566
Swissprot		P17612
Observed MW		40kDa
Reactivity		Human,Mouse
Applications		WB,IHC,IF
Conjugation		Unconjugated
Dilution		WB 1:500-1:1000, IHC 1:50-1:100, IF 1:100-1:200
Concentration		1.0 mg/mL
Buffer		Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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PKA ɑ/β CAT (Phospho-Thr197) Antibody

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