Arrestin 1 (Phospho-Ser412) Antibody

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RDSA62373
Velikost balení:	100μL
Cena bez DPH:	9 274,00 Kč
Dostupnost:	NA OBJEDNÁNÍ

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This is a Arrestin 1 (Phospho-Ser412) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein;the binding appears to require additional receptor determinants exposed only in the active receptor conformation.

Technická specifikace

Clonality		Polyclonal
Purification Method		Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Isotype		IgG
Host		Rabbit
Immunogen		Peptide sequence around phosphorylation site of Serine 412 (T-G-S(p)-P-Q) derived from Human Arrestin 1.
Gene ID		408
Swissprot		P49407
Observed MW		50kDa
Reactivity		Human
Applications		WB,IHC
Conjugation		Unconjugated
Dilution		WB 1:500-1:1000, IHC 1:50-1:100
Concentration		1.0 mg/mL
Buffer		Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Arrestin 1 (Phospho-Ser412) Antibody

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