PDHK1(Phospho-Tyr243) Antibody

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RDSA62364
Velikost balení:	100μL
Cena bez DPH:	9 274,00 Kč
Dostupnost:	NA OBJEDNÁNÍ

	Vložit do košíku

Zobrazovat ceny: bez DPH / včetně DPH

This is a PDHK1(Phospho-Tyr243) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.

Technická specifikace

Clonality		Polyclonal
Purification Method		Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Isotype		IgG
Host		Rabbit
Immunogen		Peptide sequence around phosphorylation site of tyrosine 243(D-L-Y(p)-Y-I) derived from Human PDHK1.
Gene ID		5163
Swissprot		Q15118
Calculated MW		49kDa
Reactivity		Human,Rat
Applications		WB
Conjugation		Unconjugated
Dilution		WB 1:500-1:1000
Concentration		1.0 mg/mL
Buffer		Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Vážíme si vašeho soukromí

Nezbytné/funkční

Analytické

Marketingové

PDHK1(Phospho-Tyr243) Antibody

Související produkty + doporučené příslušenství