DLC1 (Phospho-Ser986) Antibody

Dodavatel: Reddot Biotech USA Inc.
Teplota skladování: Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo: RDSA62359
Velikost balení: 100μL
Cena bez DPH: 9 274,00 Kč
Dostupnost: NA OBJEDNÁNÍ
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Zobrazovat ceny: bez DPH / včetně DPH
This is a DLC1 (Phospho-Ser986) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
ClonalityPolyclonal
Purification MethodAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
IsotypeIgG
HostRabbit
ImmunogenPeptide sequence around phosphorylation site of serine 986 (R-D-S(p)-G-V) derived from Human DLC1.
Gene ID10395
SwissprotQ96QB1
ReactivityHuman
ApplicationsWB
ConjugationUnconjugated
DilutionWB 1:500-1:1000
Concentration1.0 mg/mL
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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RDSA62359