Cdc25B(Phospho-Ser149) Antibody

Dodavatel: Reddot Biotech USA Inc.
Teplota skladování: Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo: RDSA62335
Velikost balení: 100μL
Cena bez DPH: 9 274,00 Kč
Dostupnost: NA OBJEDNÁNÍ
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Zobrazovat ceny: bez DPH / včetně DPH
This is a Cdc25B(Phospho-Ser149) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
ClonalityPolyclonal
Purification MethodAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
IsotypeIgG
HostRabbit
ImmunogenPeptide sequence around phosphorylation site of Serine 149 (F-R-S(p)-L-P) derived from Mouse Cdc25B.
Gene ID12531
SwissprotP30306
ReactivityMouse
ApplicationsWB
ConjugationUnconjugated
DilutionWB 1:500-1:1000
Concentration1.0 mg/mL
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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RDSA62335