ABL1/2 (phospho-Tyr393/439) Antibody

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RDSA62319
Velikost balení:	100μL
Cena bez DPH:	9 274,00 Kč
Dostupnost:	NA OBJEDNÁNÍ

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This is a ABL1/2 (phospho-Tyr393/439) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.

Technická specifikace

Clonality		Polyclonal
Purification Method		Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Isotype		IgG
Host		Rabbit
Immunogen		Peptide sequence around phosphorylation site of tyrosine 393/439 (D-T-Y(p)-T-A) derived from Human ABL1/2.
Gene ID		25
Swissprot		P00519
Reactivity		Human,Mouse
Applications		WB,IHC,IF
Conjugation		Unconjugated
Dilution		WB 1:500-1:1000, IHC 1:50-1:100, IF 1:100-1:200
Concentration		1.0 mg/mL
Buffer		Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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ABL1/2 (phospho-Tyr393/439) Antibody

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