PI3 Kinase p85/p55 (phospho-Tyr467/199)Antibody
| Dodavatel: | Reddot Biotech USA Inc. | |||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||
| Katalogové číslo: | RDSA62309 | |||
| Velikost balení: | 100μL | |||
| Cena bez DPH: | 9 274,00 Kč | |||
| Dostupnost: | NA OBJEDNÁNÍ | |||
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Vložit do košíku | |||
This is a PI3 Kinase p85/p55 (phospho-Tyr467/199) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1./Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
| Clonality | Polyclonal | |
| Purification Method | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide. | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 467 (L-Y(p)-E-E-Y) derived from Human PI3 Kinase p85/p55. | |
| Gene ID | 5295 | |
| Swissprot | P27986 | |
| Observed MW | 55,85kDa | |
| Reactivity | Human,Mouse,Rat | |
| Applications | WB,IF | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:500-1:1000, IF 1:100-1:500 | |
| Concentration | 1.0 mg/mL | |
| Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
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RDSA62309