PKCth(Phospho-Ser695) Antibody

Dodavatel: Reddot Biotech USA Inc.
Teplota skladování: Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo: RDSA62168
Velikost balení: 100μL
Cena bez DPH: 9 274,00 Kč
Dostupnost: NA OBJEDNÁNÍ
Vložit do košíku
Zobrazovat ceny: bez DPH / včetně DPH
This is a PKCth(Phospho-Ser695) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
ClonalityPolyclonal
Purification MethodAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
IsotypeIgG
HostRabbit
ImmunogenPeptide sequence around phosphorylation site of serine 695 (N-F-S(p)-F-M) derived from Human PKCth.
Gene ID5588
SwissprotQ04759
ReactivityHuman
ApplicationsWB,IHC
ConjugationUnconjugated
DilutionWB 1:500, IHC 1:50-1:100
Concentration1.0 mg/mL
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
0
RDSA62168