HDAC8(Phospho-Ser39) Antibody

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RDSA62129
Velikost balení:	100μL
Cena bez DPH:	9 274,00 Kč
Dostupnost:	NA OBJEDNÁNÍ

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Zobrazovat ceny: bez DPH / včetně DPH

This is a HDAC8(Phospho-Ser39) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Technická specifikace

Clonality		Polyclonal
Purification Method		Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Isotype		IgG
Host		Rabbit
Immunogen		Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V) derived from Human HDAC8.
Gene ID		55869
Swissprot		Q9BY41
Reactivity		Human
Applications		IHC,IF
Conjugation		Unconjugated
Dilution		IHC 1:50-1:100, IF 1:100-1:200
Concentration		1.0 mg/mL
Buffer		Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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HDAC8(Phospho-Ser39) Antibody

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