Smad2 Monoclonal Antibody

Dodavatel: Reddot Biotech USA Inc.
Teplota skladování: Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo: RDSA55167
Velikost balení: 100μL
Cena bez DPH: 8 964,00 Kč
Dostupnost: NA OBJEDNÁNÍ
Vložit do košíku
Zobrazovat ceny: bez DPH / včetně DPH
This is a Smad2 Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases.Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and,on formation of the SMAD2/SMAD4 complex,activates transcription.May act as a tumor suppressor in colorectal carcinoma.Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
ClonalityMonoclonal
IsotypeIgG1
HostMouse
ImmunogenPurified recombinant human SMAD2 protein fragments expressed in E.coli.
Gene ID4087
SwissprotQ15796
Observed MW60kDa
ReactivityHuman
ApplicationsWB,ICC
ConjugationUnconjugated
DilutionWB 1:500, ICC 1:100
Bufferascites
0
RDSA55167