Phospho-PAK1 (Thr212) Polyclonal Antibody
| Dodavatel: | Reddot Biotech USA Inc. | |||||||||||||||||||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||||||||||||||||||
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This is a Phospho-PAK1 (Thr212) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
| Clonality | Polyclonal | |
| Purification Method | Affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Synthesized peptide derived from human PAKα around the phosphorylation site of Thr212 | |
| Swissprot | Q13153 | |
| Calculated MW | 61 kDa | |
| Observed MW | 65 kDa | |
| Reactivity | Human,Mouse,Rat | |
| Applications | WB,IHC-p,ELISA | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000 | |
| Concentration | 1 mg/mL | |
| Buffer | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
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