Phospho-IkB alpha (Ser32/S36) Polyclonal Antibody
| Dodavatel: | Reddot Biotech USA Inc. | |||||||||||||||||||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||||||||||||||||||
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This is a Phospho-IkB alpha (Ser32/S36) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
| Clonality | Polyclonal | |
| Purification Method | Affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Synthesized peptide derived from human IκB-α around the phosphorylation site of Ser32/36 | |
| Swissprot | P25963 | |
| Calculated MW | 36 kDa | |
| Observed MW | 34 kDa | |
| Reactivity | Human,Mouse,Rat,Monkey | |
| Applications | WB,IHC-p,IF,ELISA | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000 | |
| Concentration | 1 mg/mL | |
| Buffer | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
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