Phospho-CHEK2 (Thr68) Polyclonal Antibody

Dodavatel: Reddot Biotech USA Inc.
Teplota skladování: Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo: RD85823A/120
Velikost balení: 120μL
Cena bez DPH: 9 274,00 Kč
Dostupnost: NA OBJEDNÁNÍ
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Zobrazovat ceny: bez DPH / včetně DPH
This is a Phospho-CHEK2 (Thr68) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.
ClonalityPolyclonal
Purification MethodAffinity purification
IsotypeIgG
HostRabbit
ImmunogenSynthesized peptide derived from human Chk2 around the phosphorylation site of Thr68
SwissprotO96017
Calculated MW61 kDa
Observed MW61 kDa
ReactivityHuman,Mouse,Rat
ApplicationsWB,IHC-p,IF,ELISA
ConjugationUnconjugated
DilutionWB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000-1:20000
Concentration1 mg/mL
BufferPBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
0
RD85823A/120