PARP1 Polyclonal Antibody
| Dodavatel: | Reddot Biotech USA Inc. | |||||||||||||||||||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||||||||||||||||||
| Katalogové číslo: |
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This is a PARP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
| Clonality | Polyclonal | |
| Purification Method | Affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Synthetic peptide of human PARP1 | |
| Swissprot | P09874 | |
| Calculated MW | 113 kDa | |
| Gene Accession | NP_001609.2 | |
| Reactivity | Human,Mouse,Rat | |
| Applications | WB,IHC,ELISA | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 | |
| Concentration | 0.2 mg/mL | |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
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