MCAM Polyclonal Antibody
| Dodavatel: | Reddot Biotech USA Inc. | |||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||
| Katalogové číslo: | RD253284A/20 | |||
| Velikost balení: | 20μL | |||
| Cena bez DPH: | 2 821,00 CZK | |||
| Dostupnost: | NA OBJEDNÁNÍ | |||
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Vložit do košíku | |||
This is a MCAM Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
CD146,also known as melanoma cell adhesion molecule (MCAM) or MUC18,originally identified as a biomarker of melanoma progression,is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally,it consists of five Ig domains,a transmembrane domain,and a cytoplasmic region. In normal adult tissue,CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis,and has been used as marker of circulating endothelium cells (CECs) .
| Clonality | Polyclonal | |
| Purification Method | Antigen affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Synthetic peptide of human MCAM | |
| Swissprot | P43121 | |
| Calculated MW | 72 kDa | |
| Observed MW | Refer to figures | |
| Gene Accession | NP006491 | |
| Reactivity | Human | |
| Applications | WB,IHC,ELISA | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000 | |
| Concentration | 1.14 mg/mL | |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
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