TPMT Polyclonal Antibody
| Dodavatel: | Reddot Biotech USA Inc. | |||||||||||||||||||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||||||||||||||||||
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This is a TPMT Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.
| Clonality | Polyclonal | |
| Purification Method | Antigen affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Fusion protein of human TPMT | |
| Swissprot | P51580 | |
| Calculated MW | 28 kDa | |
| Observed MW | Refer to figures | |
| Gene Accession | BC005339 | |
| Reactivity | Human | |
| Applications | WB,ELISA | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:500-1:2000, ELISA 1:5000-1:10000 | |
| Concentration | 0.96 mg/mL | |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
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