UBXN1 Polyclonal Antibody
| Dodavatel: | Reddot Biotech USA Inc. | |||||||||||||||||||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||||||||||||||||||
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This is a UBXN1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
| Clonality | Polyclonal | |
| Purification Method | Antigen affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Full length fusion protein | |
| Swissprot | Q04323 | |
| Calculated MW | 33 kDa | |
| Observed MW | Refer to figures | |
| Gene Accession | BC001372 | |
| Reactivity | Human,Mouse,Rat | |
| Applications | WB,IHC,ELISA | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000 | |
| Concentration | 1.2 mg/mL | |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
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