PRP19 Rabbit mAb

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RDSA66881
Velikost balení:	100μL
Cena bez DPH:	8 964,00 CZK
Dostupnost:	NA OBJEDNÁNÍ

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Zobrazovat ceny: bez DPH / včetně DPH

This is a PRP19 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex (PubMed:20595234).

Technická specifikace

Clonality		Monoclonal
Purification Method		Affinity purification
Isotype		IgG
Host		Rabbit
Immunogen		A synthesized peptide derived from human PRP19
Swissprot		Q9UMS4
Reactivity		Human,Mouse,Rat
Applications		WB,IHC,ICC/IF,FC
Conjugation		Unconjugated
Dilution		WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, FC 1:50
Buffer		Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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PRP19 Rabbit mAb

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