Notch1 Rabbit mAb

Dodavatel: Reddot Biotech USA Inc.
Teplota skladování: Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo: RDSA66603
Velikost balení: 100μL
Cena bez DPH: 8 964,00 CZK
Dostupnost: NA OBJEDNÁNÍ
Vložit do košíku
Zobrazovat ceny: bez DPH / včetně DPH
This is a Notch1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis;negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.
ClonalityMonoclonal
Purification MethodAffinity purification
IsotypeIgG
HostRabbit
ImmunogenA synthesized peptide derived from human Notch1
SwissprotP46531
ReactivityHuman,Mouse
ApplicationsWB,IHC,ICC/IF,FC
ConjugationUnconjugated
DilutionWB 1:500-1:3000, IHC 1:50-1:200, ICC/IF 1:100-1:500, FC 1:200-1:500
BufferPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
0
RDSA66603