PRAS40 Rabbit mAb
| Dodavatel: | Reddot Biotech USA Inc. | |||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||
| Katalogové číslo: | RDSA65420 | |||
| Velikost balení: | 100μL | |||
| Cena bez DPH: | 8 964,00 CZK | |||
| Dostupnost: | NA OBJEDNÁNÍ | |||
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Vložit do košíku | |||
This is a PRAS40 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
PRAS40 interacts with Raptor in mTOR complex 1 (mTORC1) in insulin-deprived cells and inhibits the activation of the mTORC1 pathway mediated by the cell cycle protein Rheb. Phosphorylation of PRAS40 by Akt at Thr246 relieves PRAS40 inhibition of mTORC1. mTORC1 in turn phosphorylates PRAS40 at Ser183.
| Clonality | Monoclonal | |
| Purification Method | Affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | A synthesized peptide derived from human PRAS40 | |
| Swissprot | Q96B36 | |
| Calculated MW | 40kDa | |
| Reactivity | Human,Mouse | |
| Applications | WB,IHC,IP,FC | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200, IP 1:50, FC 1:50 | |
| Buffer | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
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RDSA65420