KDM1/LSD1 Rabbit mAb
| Dodavatel: | Reddot Biotech USA Inc. | |||
| Teplota skladování: | Store at -20°C. Avoid freeze / thaw cycles. | |||
| Katalogové číslo: | RDSA65324 | |||
| Velikost balení: | 100μL | |||
| Cena bez DPH: | 8 964,00 CZK | |||
| Dostupnost: | NA OBJEDNÁNÍ | |||
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Vložit do košíku | |||
This is a KDM1/LSD1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes.
| Clonality | Monoclonal | |
| Purification Method | Affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | A synthesized peptide derived from human KDM1 / LSD1 | |
| Swissprot | O60341 | |
| Calculated MW | 110kDa | |
| Reactivity | Human,Mouse,Rat | |
| Applications | WB,IHC,ICC/IF,IP | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:1000-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:30 | |
| Buffer | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
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RDSA65324