LRRK2 Rabbit mAb

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RDSA65270
Velikost balení:	100μL
Cena bez DPH:	8 964,00 CZK
Dostupnost:	NA OBJEDNÁNÍ

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This is a LRRK2 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

LRRK2 positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner.

Technická specifikace

Clonality		Monoclonal
Purification Method		Affinity purification
Isotype		IgG
Host		Rabbit
Immunogen		A synthesized peptide derived from human LRRK2
Swissprot		Q5S007
Calculated MW		286kDa
Reactivity		Human,Mouse
Applications		WB,IHC,ICC/IF
Conjugation		Unconjugated
Dilution		WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200
Buffer		Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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LRRK2 Rabbit mAb

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