AML1 (Phospho-Ser435) Antibody

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RDSA62446
Velikost balení:	100μL
Cena bez DPH:	9 274,00 CZK
Dostupnost:	NA OBJEDNÁNÍ

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Zobrazovat ceny: bez DPH / včetně DPH

This is a AML1 (Phospho-Ser435) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits MYST4-dependent transcriptional activation.

Technická specifikace

Clonality		Polyclonal
Purification Method		Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Isotype		IgG
Host		Rabbit
Immunogen		Peptide sequence around phosphorylation site of Serine 435( S-N-S(p)-P-T) derived from Human AML1.
Gene ID		861
Swissprot		Q01196
Observed MW		53kDa
Reactivity		Human
Applications		WB
Conjugation		Unconjugated
Dilution		WB 1:500-1:1000
Concentration		1.0 mg/mL
Buffer		Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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AML1 (Phospho-Ser435) Antibody

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