IkB-b(Phospho-Ser23) Antibody

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RDSA62277
Velikost balení:	100μL
Cena bez DPH:	9 274,00 CZK
Dostupnost:	NA OBJEDNÁNÍ

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This is a IkB-b(Phospho-Ser23) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Technická specifikace

Clonality		Polyclonal
Purification Method		Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Isotype		IgG
Host		Rabbit
Immunogen		Peptide sequence around phosphorylation site of serine 23 (L-G-S(p)-L-G) derived from Human IkB-b.
Gene ID		4793
Swissprot		Q15653
Reactivity		Human,Mouse,Rat
Applications		WB,IHC
Conjugation		Unconjugated
Dilution		IHC 1:50-1:100
Concentration		1.0 mg/mL
Buffer		Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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IkB-b(Phospho-Ser23) Antibody

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