Pyk2(Phospho-Tyr402) Antibody

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RDSA62206
Velikost balení:	100μL
Cena bez DPH:	9 274,00 CZK
Dostupnost:	NA OBJEDNÁNÍ

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This is a Pyk2(Phospho-Tyr402) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation.

Technická specifikace

Clonality		Polyclonal
Purification Method		Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Isotype		IgG
Host		Rabbit
Immunogen		Peptide sequence around phosphorylation site of tyrosine 402 (D-I-Y(p)-A-E) derived from Human Pyk2.
Gene ID		2185
Swissprot		Q14289
Reactivity		Human,Mouse,Rat
Applications		WB,IHC,IF
Conjugation		Unconjugated
Dilution		WB 1:500-1:1000, IHC 1:50-1:100, IF 1:100-1:200
Concentration		1.0 mg/mL
Buffer		Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Pyk2(Phospho-Tyr402) Antibody

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