a-Synuclein(Phospho-Ser129) Antibody

Dodavatel: Reddot Biotech USA Inc.
Teplota skladování: Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo: RDSA62166
Velikost balení: 100μL
Cena bez DPH: 9 274,00 CZK
Dostupnost: NA OBJEDNÁNÍ
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Zobrazovat ceny: bez DPH / včetně DPH
This is a a-Synuclein(Phospho-Ser129) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
ClonalityPolyclonal
Purification MethodAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
IsotypeIgG
HostRabbit
ImmunogenPeptide sequence around phosphorylation site of serine 129 (M-P-S(p)-E-E) derived from Human a-Synuclein.
Gene ID6622
SwissprotP37840
ReactivityHuman,Mouse,Rat
ApplicationsWB
ConjugationUnconjugated
DilutionWB 1:500-1:1000
Concentration1.0 mg/mL
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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RDSA62166