IkB-α(Phospho-Tyr42) Antibody

Dodavatel: Reddot Biotech USA Inc.
Teplota skladování: Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo: RDSA62159
Velikost balení: 100μL
Cena bez DPH: 9 274,00 CZK
Dostupnost: NA OBJEDNÁNÍ
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Zobrazovat ceny: bez DPH / včetně DPH
This is a IkB-α(Phospho-Tyr42) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.
ClonalityPolyclonal
Purification MethodAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
IsotypeIgG
HostRabbit
ImmunogenPeptide sequence around phosphorylation site of tyrosine 42 (E-E-Y(p)-E-Q) derived from Human IkB-a
Gene ID4792
SwissprotP25963
ReactivityHuman,Mouse
ApplicationsWB,IHC
ConjugationUnconjugated
DilutionWB 1:500-1:1000, IHC 1:50-1:100
Concentration1.0 mg/mL
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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RDSA62159