p95/NBS1(Phospho-Ser343) Antibody

Dodavatel: Reddot Biotech USA Inc.
Teplota skladování: Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo: RDSA62061
Velikost balení: 100μL
Cena bez DPH: 9 274,00 CZK
Dostupnost: NA OBJEDNÁNÍ
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Zobrazovat ceny: bez DPH / včetně DPH
This is a p95/NBS1(Phospho-Ser343) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.
Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
ClonalityPolyclonal
Purification MethodAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
IsotypeIgG
HostRabbit
ImmunogenPeptide sequence around phosphorylation site of serine 343 (S-L-S(p)-Q-G) derived from Human p95/NBS1.
Gene ID4683
SwissprotO60934
ReactivityHuman
ApplicationsWB
ConjugationUnconjugated
DilutionWB 1:500-1:1000
Concentration1.0 mg/mL
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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RDSA62061