NPRL2 Polyclonal Antibody
| Dodavatel: | Reddot Biotech USA Inc. | ||||||||||||||
| Teplota skladování: | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. | ||||||||||||||
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This is a NPRL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
| Clonality | Polyclonal | |
| Purification Method | Affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Recombinant fusion protein of human NPRL2 | |
| Gene ID | 10641 | |
| Swissprot | Q8WTW4 | |
| Calculated MW | 29kDa/45kDa | |
| Observed MW | 45kDa | |
| Reactivity | Human,Rat | |
| Applications | WB | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:500-1:2000 | |
| Concentration | 1mg/mL | |
| Buffer | PBS with 0.01% thiomersal,50% glycerol,pH7.3. |
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