NPRL2 Polyclonal Antibody

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Katalogové číslo:	RD88592A/120
Velikost balení:	120μL
Cena bez DPH:	12 365,00 CZK
Dostupnost:	NA OBJEDNÁNÍ

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Zobrazovat ceny: bez DPH / včetně DPH

This is a NPRL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.

Technická specifikace

Clonality		Polyclonal
Purification Method		Affinity purification
Isotype		IgG
Host		Rabbit
Immunogen		Recombinant fusion protein of human NPRL2
Gene ID		10641
Swissprot		Q8WTW4
Calculated MW		29kDa/45kDa
Observed MW		45kDa
Reactivity		Human,Rat
Applications		WB
Conjugation		Unconjugated
Dilution		WB 1:500-1:2000
Concentration		1mg/mL
Buffer		PBS with 0.01% thiomersal,50% glycerol,pH7.3.

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NPRL2 Polyclonal Antibody

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