RNF185 Polyclonal Antibody
| Dodavatel: | Reddot Biotech USA Inc. | ||||||||||||||
| Teplota skladování: | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. | ||||||||||||||
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This is a RNF185 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1. Acts in the endoplasmic reticulum (ER-associated degradation (ERAD pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2.
| Clonality | Polyclonal | |
| Purification Method | Affinity purification | |
| Isotype | IgG | |
| Host | Rabbit | |
| Immunogen | Recombinant fusion protein of human RNF185 | |
| Gene ID | 91445 | |
| Swissprot | Q96GF1 | |
| Calculated MW | 86kDa/105kDa/111kDa/120kDa | |
| Observed MW | 130kDa | |
| Reactivity | Human,Mouse,Rat | |
| Applications | WB | |
| Conjugation | Unconjugated | |
| Dilution | WB 1:500-1:2000 | |
| Concentration | 1mg/mL | |
| Buffer | PBS with 0.01% thiomersal,50% glycerol,pH7.3. |
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