HN1 Polyclonal Antibody

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Katalogové číslo:	RD88477A/200
Velikost balení:	200μL
Cena bez DPH:	20 479,00 CZK
Dostupnost:	NA OBJEDNÁNÍ

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Zobrazovat ceny: bez DPH / včetně DPH

This is a HN1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation.

Technická specifikace

Clonality		Polyclonal
Purification Method		Affinity purification
Isotype		IgG
Host		Rabbit
Immunogen		Recombinant fusion protein of human HN1
Gene ID		51155
Swissprot		Q9UK76
Calculated MW		22kDa
Observed MW		23kDa
Reactivity		Human,Mouse,Rat
Applications		WB,IHC
Conjugation		Unconjugated
Dilution		WB 1:500-1:2000,IHC 1:50-1:200
Concentration		1mg/mL
Buffer		PBS with 0.01% thiomersal,50% glycerol,pH7.3.

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HN1 Polyclonal Antibody

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