HSPA2 Polyclonal Antibody

Human HSPA2 is a member of the HSPA (HSP70) family of heat-shock proteins,encoded by the gene originally described as testis-specific. Recently,it has been reported that HSPA2 can be also expressed in human somatic tissues in a cell-type specific manner. HSPA2 is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. HSPA2 is involved in sperm maturity,function and fertility. Aberrant expression of HSPA2 in testes has been connected with male infertility. Recently,HSPA2 has attracted increased interest due to its possible involvement in carcinogenesis of non-testicular tissues. This antibody well recognized the endogenous HSPA4 protein in testis and multiple cell lines. (21373891)