SMAD7 Polyclonal Antibody

Dodavatel:	Reddot Biotech USA Inc.
Teplota skladování:	Store at -20°C. Avoid freeze / thaw cycles.
Katalogové číslo:	RD80877A/60
Velikost balení:	60μL
Cena bez DPH:	7 728,00 CZK
Dostupnost:	NA OBJEDNÁNÍ

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Zobrazovat ceny: bez DPH / včetně DPH

This is a SMAD7 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.

Technická specifikace

Purification Method		Affinity purification
Isotype		IgG
Host		Rabbit
Immunogen		A synthetic peptide of human SMAD7 (NP_005895.1).
Gene ID		4092
Swissprot		O15105
Calculated MW		23 kDa/46 kDa
Observed MW		46 kDa
Reactivity		Human,Mouse,Rat
Applications		WB,IF
Conjugation		Unconjugated
Dilution		WB 1:500-1:2000 IF 1:50-1:200
Concentration		1 mg/mL
Buffer		PBS with 0.02% sodium azide, 50% glycerol, pH7.3

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SMAD7 Polyclonal Antibody

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